Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM161446'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161446 (US10124003, Ex. Compound 59 | US10835536, Ex. Comp...) Show SMILES CCN(CC)C\C=C\C(=O)N1CC(C1)n1cc(C#Cc2cc(OC)cc(OC)c2)c2c(N)ncnc12 Show InChI InChI=1S/C27H32N6O3/c1-5-31(6-2)11-7-8-24(34)32-16-21(17-32)33-15-20(25-26(28)29-18-30-27(25)33)10-9-19-12-22(35-3)14-23(13-19)36-4/h7-8,12-15,18,21H,5-6,11,16-17H2,1-4H3,(H2,28,29,30)/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.5	25
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US9108973 (2015) BindingDB Entry DOI: 10.7270/Q2XW4HJV
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161446 (US10124003, Ex. Compound 59 | US10835536, Ex. Comp...) Show SMILES CCN(CC)C\C=C\C(=O)N1CC(C1)n1cc(C#Cc2cc(OC)cc(OC)c2)c2c(N)ncnc12 Show InChI InChI=1S/C27H32N6O3/c1-5-31(6-2)11-7-8-24(34)32-16-21(17-32)33-15-20(25-26(28)29-18-30-27(25)33)10-9-19-12-22(35-3)14-23(13-19)36-4/h7-8,12-15,18,21H,5-6,11,16-17H2,1-4H3,(H2,28,29,30)/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10894048 (2021) BindingDB Entry DOI: 10.7270/Q2319ZZF
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161446 (US10124003, Ex. Compound 59 | US10835536, Ex. Comp...) Show SMILES CCN(CC)C\C=C\C(=O)N1CC(C1)n1cc(C#Cc2cc(OC)cc(OC)c2)c2c(N)ncnc12 Show InChI InChI=1S/C27H32N6O3/c1-5-31(6-2)11-7-8-24(34)32-16-21(17-32)33-15-20(25-26(28)29-18-30-27(25)33)10-9-19-12-22(35-3)14-23(13-19)36-4/h7-8,12-15,18,21H,5-6,11,16-17H2,1-4H3,(H2,28,29,30)/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10835536 (2020) BindingDB Entry DOI: 10.7270/Q23N26F5
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161446 (US10124003, Ex. Compound 59 | US10835536, Ex. Comp...) Show SMILES CCN(CC)C\C=C\C(=O)N1CC(C1)n1cc(C#Cc2cc(OC)cc(OC)c2)c2c(N)ncnc12 Show InChI InChI=1S/C27H32N6O3/c1-5-31(6-2)11-7-8-24(34)32-16-21(17-32)33-15-20(25-26(28)29-18-30-27(25)33)10-9-19-12-22(35-3)14-23(13-19)36-4/h7-8,12-15,18,21H,5-6,11,16-17H2,1-4H3,(H2,28,29,30)/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10124003 (2018) BindingDB Entry DOI: 10.7270/Q2B27XBQ
					More data for this Ligand-Target Pair