Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM161448'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161448 (US10124003, Ex. Compound 61 | US10835536, Ex. Comp...) Show SMILES COc1cc(OC)cc(c1)C#Cc1cn(C2CN(C2)C(=O)\C=C\CN2CCC(O)CC2)c2ncnc(N)c12 Show InChI InChI=1S/C28H32N6O4/c1-37-23-12-19(13-24(14-23)38-2)5-6-20-15-34(28-26(20)27(29)30-18-31-28)21-16-33(17-21)25(36)4-3-9-32-10-7-22(35)8-11-32/h3-4,12-15,18,21-22,35H,7-11,16-17H2,1-2H3,(H2,29,30,31)/b4-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	7.5	25
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US9108973 (2015) BindingDB Entry DOI: 10.7270/Q2XW4HJV
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161448 (US10124003, Ex. Compound 61 | US10835536, Ex. Comp...) Show SMILES COc1cc(OC)cc(c1)C#Cc1cn(C2CN(C2)C(=O)\C=C\CN2CCC(O)CC2)c2ncnc(N)c12 Show InChI InChI=1S/C28H32N6O4/c1-37-23-12-19(13-24(14-23)38-2)5-6-20-15-34(28-26(20)27(29)30-18-31-28)21-16-33(17-21)25(36)4-3-9-32-10-7-22(35)8-11-32/h3-4,12-15,18,21-22,35H,7-11,16-17H2,1-2H3,(H2,29,30,31)/b4-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10835536 (2020) BindingDB Entry DOI: 10.7270/Q23N26F5
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM161448 (US10124003, Ex. Compound 61 | US10835536, Ex. Comp...) Show SMILES COc1cc(OC)cc(c1)C#Cc1cn(C2CN(C2)C(=O)\C=C\CN2CCC(O)CC2)c2ncnc(N)c12 Show InChI InChI=1S/C28H32N6O4/c1-37-23-12-19(13-24(14-23)38-2)5-6-20-15-34(28-26(20)27(29)30-18-31-28)21-16-33(17-21)25(36)4-3-9-32-10-7-22(35)8-11-32/h3-4,12-15,18,21-22,35H,7-11,16-17H2,1-2H3,(H2,29,30,31)/b4-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10124003 (2018) BindingDB Entry DOI: 10.7270/Q2B27XBQ
					More data for this Ligand-Target Pair