Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM438598'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM438598 (US10618902, Compound I-279) Show SMILES COc1cc(OC)c(Cl)c(c1F)-c1cc2cnc(N[C@@H]3COC[C@@H]3NC(=O)C=C)nc2n(C)c1=O |r,wU:19.19,23.25,(9.16,-1.17,;9.16,.37,;7.82,1.14,;7.82,2.68,;6.49,3.45,;6.49,4.99,;7.82,5.76,;5.16,2.68,;3.82,3.45,;5.16,1.14,;6.49,.37,;6.49,-1.17,;3.82,.37,;2.49,1.14,;1.15,.37,;-.18,1.14,;-1.51,.37,;-1.51,-1.17,;-2.85,-1.94,;-4.18,-1.17,;-4.34,.36,;-5.85,.68,;-6.62,-.65,;-5.59,-1.8,;-5.91,-3.3,;-7.37,-3.78,;-8.52,-2.75,;-7.69,-5.28,;-9.16,-5.76,;-.18,-1.94,;1.15,-1.17,;2.49,-1.94,;2.49,-3.48,;3.82,-1.17,;5.16,-1.94,)| Show InChI InChI=1S/C23H23ClFN5O5/c1-5-17(31)27-13-9-35-10-14(13)28-23-26-8-11-6-12(22(32)30(2)21(11)29-23)18-19(24)15(33-3)7-16(34-4)20(18)25/h5-8,13-14H,1,9-10H2,2-4H3,(H,27,31)(H,26,28,29)/t13-,14+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	563	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human tagged FGFR2 using Y10-Sox as substrate in presence of 250 uM ATP by Omnia kinase method				Citation and Details Article DOI: 10.1021/acsmedchemlett.9b00601 BindingDB Entry DOI: 10.7270/Q2CN77NN
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM438598 (US10618902, Compound I-279) Show SMILES COc1cc(OC)c(Cl)c(c1F)-c1cc2cnc(N[C@@H]3COC[C@@H]3NC(=O)C=C)nc2n(C)c1=O |r,wU:19.19,23.25,(9.16,-1.17,;9.16,.37,;7.82,1.14,;7.82,2.68,;6.49,3.45,;6.49,4.99,;7.82,5.76,;5.16,2.68,;3.82,3.45,;5.16,1.14,;6.49,.37,;6.49,-1.17,;3.82,.37,;2.49,1.14,;1.15,.37,;-.18,1.14,;-1.51,.37,;-1.51,-1.17,;-2.85,-1.94,;-4.18,-1.17,;-4.34,.36,;-5.85,.68,;-6.62,-.65,;-5.59,-1.8,;-5.91,-3.3,;-7.37,-3.78,;-8.52,-2.75,;-7.69,-5.28,;-9.16,-5.76,;-.18,-1.94,;1.15,-1.17,;2.49,-1.94,;2.49,-3.48,;3.82,-1.17,;5.16,-1.94,)| Show InChI InChI=1S/C23H23ClFN5O5/c1-5-17(31)27-13-9-35-10-14(13)28-23-26-8-11-6-12(22(32)30(2)21(11)29-23)18-19(24)15(33-3)7-16(34-4)20(18)25/h5-8,13-14H,1,9-10H2,2-4H3,(H,27,31)(H,26,28,29)/t13-,14+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	617	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FGFR2 (unknown origin) expressed in KATO -III cells assessed as autophosphorylation after 1 hr incubation measured by Mesoscale discove...				Citation and Details Article DOI: 10.1021/acsmedchemlett.9b00601 BindingDB Entry DOI: 10.7270/Q2CN77NN
					More data for this Ligand-Target Pair