Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM478146'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM478146 (US10894048, Ex Comp 66) Show SMILES COC(=O)[C@@H]1C[C@@H](CN1C(=O)C=C)n1nc(C#Cc2cc(OC)cc(OC)c2)c2c(N)ncnc12 |r| Show InChI InChI=1S/C24H24N6O5/c1-5-20(31)29-12-15(10-19(29)24(32)35-4)30-23-21(22(25)26-13-27-23)18(28-30)7-6-14-8-16(33-2)11-17(9-14)34-3/h5,8-9,11,13,15,19H,1,10,12H2,2-4H3,(H2,25,26,27)/t15-,19-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.300	n/a	n/a	n/a	n/a	n/a	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description When setting conditions for the measurement of the inhibitory effect of the compounds on FGFR2 kinase activity, FL-Peptide 22 (Caliper Life Sciences,...				US Patent US10894048 (2021) BindingDB Entry DOI: 10.7270/Q2319ZZF
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