Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM50166652'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50166652 (CHEMBL3798924) Show SMILES COCCNc1ccc2c(Nc3cc(CCc4cc(OC)cc(OC)c4)[nH]n3)ncnc2c1 Show InChI InChI=1S/C24H28N6O3/c1-31-9-8-25-17-6-7-21-22(12-17)26-15-27-24(21)28-23-13-18(29-30-23)5-4-16-10-19(32-2)14-20(11-16)33-3/h6-7,10-15,25H,4-5,8-9H2,1-3H3,(H2,26,27,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant FGFR2 (unknown origin) using (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISA				Bioorg Med Chem Lett 26: 2594-9 (2016) Article DOI: 10.1016/j.bmcl.2016.04.028 BindingDB Entry DOI: 10.7270/Q20C4XNM
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50166652 (CHEMBL3798924) Show SMILES COCCNc1ccc2c(Nc3cc(CCc4cc(OC)cc(OC)c4)[nH]n3)ncnc2c1 Show InChI InChI=1S/C24H28N6O3/c1-31-9-8-25-17-6-7-21-22(12-17)26-15-27-24(21)28-23-13-18(29-30-23)5-4-16-10-19(32-2)14-20(11-16)33-3/h6-7,10-15,25H,4-5,8-9H2,1-3H3,(H2,26,27,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences (CAS) Curated by ChEMBL					Assay Description Inhibition of recombinant FGFR2 in human SNU16 cells assessed as suppression of cell proliferation after 72 hrs by SRB/CCK-8 assay				Bioorg Med Chem Lett 26: 2594-9 (2016) Article DOI: 10.1016/j.bmcl.2016.04.028 BindingDB Entry DOI: 10.7270/Q20C4XNM
					More data for this Ligand-Target Pair