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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM50260187'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 2


(Homo sapiens (Human))
BDBM50260187
PNG
(CHEMBL4096738)
Show SMILES COc1cc(OC)c(Cl)c(N2Cc3cnc(NC4CCOC4)nc3N(C3CCN(CC3)C(=O)\C=C\CN(C)C)C2=O)c1Cl
Show InChI InChI=1S/C29H37Cl2N7O5/c1-35(2)10-5-6-23(39)36-11-7-20(8-12-36)38-27-18(15-32-28(34-27)33-19-9-13-43-17-19)16-37(29(38)40)26-24(30)21(41-3)14-22(42-4)25(26)31/h5-6,14-15,19-20H,7-13,16-17H2,1-4H3,(H,32,33,34)/b6-5+
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PC cid
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Similars

Article
PubMed
n/an/a 3.60n/an/an/an/an/an/a



Guangzhou Institutes of Biomedicine and Health

Curated by ChEMBL


Assay Description
Inhibition of human recombinant cytoplasmic His-tagged FGFR2 (403 to 822 residues) expressed in baculovirus using Tyr-4 peptide after 1 hr by FRET-ba...


Eur J Med Chem 135: 531-543 (2017)


Article DOI: 10.1016/j.ejmech.2017.04.049
BindingDB Entry DOI: 10.7270/Q2K076QF
More data for this
Ligand-Target Pair