Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 3' and Ligand = 'BDBM128422'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM128422 (US8796244, 1) Show SMILES FC(F)(F)CNC(=O)Nc1cccc(c1)-c1cnc2cc(ccn12)-c1nnc(s1)C1CCCO1 Show InChI InChI=1S/C22H19F3N6O2S/c23-22(24,25)12-27-21(32)28-15-4-1-3-13(9-15)16-11-26-18-10-14(6-7-31(16)18)19-29-30-20(34-19)17-5-2-8-33-17/h1,3-4,6-7,9-11,17H,2,5,8,12H2,(H2,27,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.830	n/a	n/a	n/a	n/a	8.0	25
Astex Therapeutics Ltd US Patent					Assay Description Enzymes (from Upstate) were prepared at 2× final concentration in 1× kinase assay buffer (Table 1). Enzymes were then incubated with test compounds, ...				US Patent US8796244 (2014) BindingDB Entry DOI: 10.7270/Q20C4TFP
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