Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fibroblast growth factor receptor 4 (Homo sapiens (Human)) | BDBM161389 (US10124003, Ref. Ex. Compound 3 | US10835536, Ex. ...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description Purified recombinant human FGFR4 protein was purchased from Carna Biosciences, Inc. When setting conditions for the measurement of the inhibitory ef... | US Patent US9108973 (2015) BindingDB Entry DOI: 10.7270/Q2XW4HJV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 4 (Homo sapiens (Human)) | BDBM161389 (US10124003, Ref. Ex. Compound 3 | US10835536, Ex. ...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | US Patent | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Taiho Pharmaceutical Co., Ltd. US Patent | Assay Description The inhibitory effect of the compounds on FGFR4 kinase activity was measured according to the method of Test Example 3. Purified recombinant human FG... | US Patent US10894048 (2021) BindingDB Entry DOI: 10.7270/Q2319ZZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 4 (Homo sapiens (Human)) | BDBM161389 (US10124003, Ref. Ex. Compound 3 | US10835536, Ex. ...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 4 (Homo sapiens (Human)) | BDBM161389 (US10124003, Ref. Ex. Compound 3 | US10835536, Ex. ...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 5.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human FGFR4 (445 to 753 residues) expressed in Escherichia coli BL21 (DE3) by HTRF assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00174 BindingDB Entry DOI: 10.7270/Q2P84GS6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 4 (Homo sapiens (Human)) | BDBM161389 (US10124003, Ref. Ex. Compound 3 | US10835536, Ex. ...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | n/a | n/a | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fibroblast growth factor receptor 4 (Homo sapiens (Human)) | BDBM161389 (US10124003, Ref. Ex. Compound 3 | US10835536, Ex. ...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 8.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01719 BindingDB Entry DOI: 10.7270/Q2HQ43WX | ||||||||||||
More data for this Ligand-Target Pair |