Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 4' and Ligand = 'BDBM209291'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM209291 (US9266883, 49) Show SMILES OCc1cc2CCCN(C(=O)Nc3cc(O[C@@H]4CCOC4)c(cn3)C#N)c2nc1C=O |r| Show InChI InChI=1S/C21H21N5O5/c22-8-15-9-23-19(7-18(15)31-16-3-5-30-12-16)25-21(29)26-4-1-2-13-6-14(10-27)17(11-28)24-20(13)26/h6-7,9,11,16,27H,1-5,10,12H2,(H,23,25,29)/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant non-phosphorylated FGFR4 kinase domain (442 to 753) (unknown origin) expressed in Sf9 insect cells using 5-Fluo-Ahx-KKKKEEI...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01019 BindingDB Entry DOI: 10.7270/Q2FB56MJ
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Mus musculus)	BDBM209291 (US9266883, 49) Show SMILES OCc1cc2CCCN(C(=O)Nc3cc(O[C@@H]4CCOC4)c(cn3)C#N)c2nc1C=O |r| Show InChI InChI=1S/C21H21N5O5/c22-8-15-9-23-19(7-18(15)31-16-3-5-30-12-16)25-21(29)26-4-1-2-13-6-14(10-27)17(11-28)24-20(13)26/h6-7,9,11,16,27H,1-5,10,12H2,(H,23,25,29)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FGFR4 in mouse BAF3 cells assessed as decrease in FGFR4 phosphorylation incubated for 40 mins				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01019 BindingDB Entry DOI: 10.7270/Q2FB56MJ
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Mus musculus)	BDBM209291 (US9266883, 49) Show SMILES OCc1cc2CCCN(C(=O)Nc3cc(O[C@@H]4CCOC4)c(cn3)C#N)c2nc1C=O |r| Show InChI InChI=1S/C21H21N5O5/c22-8-15-9-23-19(7-18(15)31-16-3-5-30-12-16)25-21(29)26-4-1-2-13-6-14(10-27)17(11-28)24-20(13)26/h6-7,9,11,16,27H,1-5,10,12H2,(H,23,25,29)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FGFR4 in mouse BAF3 cells assessed as reduction in cell viability incubated for 2 days by cell proliferation assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01019 BindingDB Entry DOI: 10.7270/Q2FB56MJ
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM209291 (US9266883, 49) Show SMILES OCc1cc2CCCN(C(=O)Nc3cc(O[C@@H]4CCOC4)c(cn3)C#N)c2nc1C=O |r| Show InChI InChI=1S/C21H21N5O5/c22-8-15-9-23-19(7-18(15)31-16-3-5-30-12-16)25-21(29)26-4-1-2-13-6-14(10-27)17(11-28)24-20(13)26/h6-7,9,11,16,27H,1-5,10,12H2,(H,23,25,29)/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of reporter probe from human recombinant FGFR4 (391 to 802) expressed in Baculovirus infected Sf9 cells measured after 30 mins by proter...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01019 BindingDB Entry DOI: 10.7270/Q2FB56MJ
					More data for this Ligand-Target Pair