Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 4' and Ligand = 'BDBM339850'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM339850 (US9757364, Compound 49) Show SMILES COc1cc(OC)c(F)c(N(Cc2nnc[nH]2)c2ccc3ncc(cc3n2)-c2cnn(C)c2)c1F Show InChI InChI=1S/C23H20F2N8O2/c1-32-10-14(9-29-32)13-6-16-15(26-8-13)4-5-20(30-16)33(11-19-27-12-28-31-19)23-21(24)17(34-2)7-18(35-3)22(23)25/h4-10,12H,11H2,1-3H3,(H,27,28,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.933	n/a	n/a	n/a	n/a	n/a	n/a
ASTEX THERAPEUTICS LTD US Patent					Assay Description In a final reaction volume of 30 μL, FGFR4 (h) (60 ng/ml) was incubated with 50 mM HEPES pH 7.5, 6 mM MnCl2, 1 mM DTT, 0.1 mM Na3VO4, 0.01% Trit...				US Patent US9757364 (2017) BindingDB Entry DOI: 10.7270/Q2SB47VT
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