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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Flap endonuclease 1' and Ligand = 'BDBM167038'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Flap endonuclease 1


(Homo sapiens (Human))
BDBM167038
PNG
(US9073876, 124 | US9732093, Compound 124)
Show SMILES Nc1cnc(cn1)-c1ccc(C2CCC2)c(Oc2ccnc(n2)C(F)(F)F)c1F
Show InChI InChI=1S/C19H15F4N5O/c20-16-12(13-8-27-14(24)9-26-13)5-4-11(10-2-1-3-10)17(16)29-15-6-7-25-18(28-15)19(21,22)23/h4-10H,1-3H2,(H2,24,27)
PDB
MMDB

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PC cid
PC sid
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US Patent
2.80n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent




US Patent US9732093 (2017)


BindingDB Entry DOI: 10.7270/Q2NV9MCX
More data for this
Ligand-Target Pair
Flap endonuclease 1


(Homo sapiens (Human))
BDBM167038
PNG
(US9073876, 124 | US9732093, Compound 124)
Show SMILES Nc1cnc(cn1)-c1ccc(C2CCC2)c(Oc2ccnc(n2)C(F)(F)F)c1F
Show InChI InChI=1S/C19H15F4N5O/c20-16-12(13-8-27-14(24)9-26-13)5-4-11(10-2-1-3-10)17(16)29-15-6-7-25-18(28-15)19(21,22)23/h4-10H,1-3H2,(H2,24,27)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
3n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent




US Patent US9732093 (2017)


BindingDB Entry DOI: 10.7270/Q2NV9MCX
More data for this
Ligand-Target Pair