Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Flap endonuclease 1' and Ligand = 'BDBM167038'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Flap endonuclease 1 (Homo sapiens (Human))	BDBM167038 (US9073876, 124 | US9732093, Compound 124) Show SMILES Nc1cnc(cn1)-c1ccc(C2CCC2)c(Oc2ccnc(n2)C(F)(F)F)c1F Show InChI InChI=1S/C19H15F4N5O/c20-16-12(13-8-27-14(24)9-26-13)5-4-11(10-2-1-3-10)17(16)29-15-6-7-25-18(28-15)19(21,22)23/h4-10H,1-3H2,(H2,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9732093 (2017) BindingDB Entry DOI: 10.7270/Q2NV9MCX
					More data for this Ligand-Target Pair
Flap endonuclease 1 (Homo sapiens (Human))	BDBM167038 (US9073876, 124 | US9732093, Compound 124) Show SMILES Nc1cnc(cn1)-c1ccc(C2CCC2)c(Oc2ccnc(n2)C(F)(F)F)c1F Show InChI InChI=1S/C19H15F4N5O/c20-16-12(13-8-27-14(24)9-26-13)5-4-11(10-2-1-3-10)17(16)29-15-6-7-25-18(28-15)19(21,22)23/h4-10H,1-3H2,(H2,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9732093 (2017) BindingDB Entry DOI: 10.7270/Q2NV9MCX
					More data for this Ligand-Target Pair