Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Flap endonuclease 1' and Ligand = 'BDBM167232'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Flap endonuclease 1 (Homo sapiens (Human))	BDBM167232 (US9073876, 313 | US9732093, Compound 313) Show SMILES Nc1cnc(cn1)-c1ccc(C2CCC2)c(Oc2ncc(cn2)-c2cnc(N)nc2)c1F Show InChI InChI=1S/C22H19FN8O/c23-19-16(17-10-27-18(24)11-26-17)5-4-15(12-2-1-3-12)20(19)32-22-30-8-14(9-31-22)13-6-28-21(25)29-7-13/h4-12H,1-3H2,(H2,24,27)(H2,25,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9732093 (2017) BindingDB Entry DOI: 10.7270/Q2NV9MCX
					More data for this Ligand-Target Pair
Flap endonuclease 1 (Homo sapiens (Human))	BDBM167232 (US9073876, 313 | US9732093, Compound 313) Show SMILES Nc1cnc(cn1)-c1ccc(C2CCC2)c(Oc2ncc(cn2)-c2cnc(N)nc2)c1F Show InChI InChI=1S/C22H19FN8O/c23-19-16(17-10-27-18(24)11-26-17)5-4-15(12-2-1-3-12)20(19)32-22-30-8-14(9-31-22)13-6-28-21(25)29-7-13/h4-12H,1-3H2,(H2,24,27)(H2,25,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9732093 (2017) BindingDB Entry DOI: 10.7270/Q2NV9MCX
					More data for this Ligand-Target Pair