Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Flap endonuclease 1' and Ligand = 'BDBM168991'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Flap endonuclease 1 (Homo sapiens (Human))	BDBM168991 (US9079866, 392 | US9745328, Compound 392 | US98848...) Show SMILES Fc1cc(ccc1-c1cnc2NCCOc2c1)-c1ccccc1S(=O)(=O)N1CCS(=O)(=O)CC1 Show InChI InChI=1S/C23H22FN3O5S2/c24-20-13-16(5-6-18(20)17-14-21-23(26-15-17)25-7-10-32-21)19-3-1-2-4-22(19)34(30,31)27-8-11-33(28,29)12-9-27/h1-6,13-15H,7-12H2,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The FLAP binding assay is performed in HTRF format (homogeneous time resolved fluorescence). FLAP-containing membranes (1 μg/well final for huma...				US Patent US9745328 (2017) BindingDB Entry DOI: 10.7270/Q2H13446
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