Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Free fatty acid receptor 1' and Ligand = 'BDBM50267048'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50267048 (CHEMBL4075190) Show SMILES Cc1ccccc1Cc1ccc(cc1)N1CCC[C@@]1(C)CC(O)=O |r| Show InChI InChI=1S/C21H25NO2/c1-16-6-3-4-7-18(16)14-17-8-10-19(11-9-17)22-13-5-12-21(22,2)15-20(23)24/h3-4,6-11H,5,12-15H2,1-2H3,(H,23,24)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Binding affinity to human GPR40 expressed in HEK293 cell membranes after 1 hr by radioligand displacement based scintillation counting method				J Med Chem 60: 1417-1431 (2017) Article DOI: 10.1021/acs.jmedchem.6b01559 BindingDB Entry DOI: 10.7270/Q25X2CD5
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50267048 (CHEMBL4075190) Show SMILES Cc1ccccc1Cc1ccc(cc1)N1CCC[C@@]1(C)CC(O)=O |r| Show InChI InChI=1S/C21H25NO2/c1-16-6-3-4-7-18(16)14-17-8-10-19(11-9-17)22-13-5-12-21(22,2)15-20(23)24/h3-4,6-11H,5,12-15H2,1-2H3,(H,23,24)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human GPR40 expressed in CHO-A12 cells assessed as increase in intracellular calcium flux measured for 100 secs by FLIPR assay				J Med Chem 60: 1417-1431 (2017) Article DOI: 10.1021/acs.jmedchem.6b01559 BindingDB Entry DOI: 10.7270/Q25X2CD5
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Mus musculus)	BDBM50267048 (CHEMBL4075190) Show SMILES Cc1ccccc1Cc1ccc(cc1)N1CCC[C@@]1(C)CC(O)=O |r| Show InChI InChI=1S/C21H25NO2/c1-16-6-3-4-7-18(16)14-17-8-10-19(11-9-17)22-13-5-12-21(22,2)15-20(23)24/h3-4,6-11H,5,12-15H2,1-2H3,(H,23,24)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at GPR40 in mouse STC1 cells assessed as induction of GLP-1 secretion measured after 1 hr by HTRF assay				J Med Chem 60: 1417-1431 (2017) Article DOI: 10.1021/acs.jmedchem.6b01559 BindingDB Entry DOI: 10.7270/Q25X2CD5
					More data for this Ligand-Target Pair