Compile Data Set for Download or QSAR

Found 6 hits Enz. Inhib. hit(s) with Target = 'Free fatty acid receptor 1' and Ligand = 'BDBM50382542'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50382542 (CHEMBL2022244) Show SMILES Cc1cccc(C)c1-c1cccc(COc2ccc3C(CC(O)=O)CCCc3c2)c1 Show InChI InChI=1S/C27H28O3/c1-18-6-3-7-19(2)27(18)23-11-4-8-20(14-23)17-30-24-12-13-25-21(15-24)9-5-10-22(25)16-26(28)29/h3-4,6-8,11-15,22H,5,9-10,16-17H2,1-2H3,(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Displacement of 3-[4-({2',6'-dimethyl-6-[(4-[3H])-phenylmethoxy]biphenyl-3-yl}methoxy)phenyl] propanoic acid from human GPR40 receptor expressed in C...				J Med Chem 55: 1538-52 (2012) Article DOI: 10.1021/jm2012968 BindingDB Entry DOI: 10.7270/Q2HQ40X4
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50382542 (CHEMBL2022244) Show SMILES Cc1cccc(C)c1-c1cccc(COc2ccc3C(CC(O)=O)CCCc3c2)c1 Show InChI InChI=1S/C27H28O3/c1-18-6-3-7-19(2)27(18)23-11-4-8-20(14-23)17-30-24-12-13-25-21(15-24)9-5-10-22(25)16-26(28)29/h3-4,6-8,11-15,22H,5,9-10,16-17H2,1-2H3,(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of 3-[4-({2',6'-dimethyl-6-[(4-[3H])phenylmethoxy]biphenyl-3-yl}methoxy)phenyl]propanoic acid from human GPR40 expressed in CHO membrane...				ACS Med Chem Lett 1: 290-294 (2010) Article DOI: 10.1021/ml1000855 BindingDB Entry DOI: 10.7270/Q29G5NZJ
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Rattus norvegicus)	BDBM50382542 (CHEMBL2022244) Show SMILES Cc1cccc(C)c1-c1cccc(COc2ccc3C(CC(O)=O)CCCc3c2)c1 Show InChI InChI=1S/C27H28O3/c1-18-6-3-7-19(2)27(18)23-11-4-8-20(14-23)17-30-24-12-13-25-21(15-24)9-5-10-22(25)16-26(28)29/h3-4,6-8,11-15,22H,5,9-10,16-17H2,1-2H3,(H,28,29)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of 3-[4-({2',6'-dimethyl-6-[(4-[3H])phenylmethoxy]biphenyl-3-yl}methoxy)phenyl]propanoic acid from rat GPR40 expressed in CHO membranes ...				ACS Med Chem Lett 1: 290-294 (2010) Article DOI: 10.1021/ml1000855 BindingDB Entry DOI: 10.7270/Q29G5NZJ
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Rattus norvegicus)	BDBM50382542 (CHEMBL2022244) Show SMILES Cc1cccc(C)c1-c1cccc(COc2ccc3C(CC(O)=O)CCCc3c2)c1 Show InChI InChI=1S/C27H28O3/c1-18-6-3-7-19(2)27(18)23-11-4-8-20(14-23)17-30-24-12-13-25-21(15-24)9-5-10-22(25)16-26(28)29/h3-4,6-8,11-15,22H,5,9-10,16-17H2,1-2H3,(H,28,29)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Displacement of 3-[4-({2',6'-dimethyl-6-[(4-[3H])-phenylmethoxy]biphenyl-3-yl}methoxy)phenyl] propanoic acid from rat GPR40 receptor expressed in CHO...				J Med Chem 55: 1538-52 (2012) Article DOI: 10.1021/jm2012968 BindingDB Entry DOI: 10.7270/Q2HQ40X4
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50382542 (CHEMBL2022244) Show SMILES Cc1cccc(C)c1-c1cccc(COc2ccc3C(CC(O)=O)CCCc3c2)c1 Show InChI InChI=1S/C27H28O3/c1-18-6-3-7-19(2)27(18)23-11-4-8-20(14-23)17-30-24-12-13-25-21(15-24)9-5-10-22(25)16-26(28)29/h3-4,6-8,11-15,22H,5,9-10,16-17H2,1-2H3,(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Agonist activity at human GR40 receptor expressed in CHO cells assessed as increase in intracellular calcium concentration after 90 secs by FLIPR ass...				J Med Chem 55: 1538-52 (2012) Article DOI: 10.1021/jm2012968 BindingDB Entry DOI: 10.7270/Q2HQ40X4
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50382542 (CHEMBL2022244) Show SMILES Cc1cccc(C)c1-c1cccc(COc2ccc3C(CC(O)=O)CCCc3c2)c1 Show InChI InChI=1S/C27H28O3/c1-18-6-3-7-19(2)27(18)23-11-4-8-20(14-23)17-30-24-12-13-25-21(15-24)9-5-10-22(25)16-26(28)29/h3-4,6-8,11-15,22H,5,9-10,16-17H2,1-2H3,(H,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Agonist activity at human GPR40 expressed in CHO cells assessed as calcium influx by FLIPR assay in presence of 0.1 % BSA				ACS Med Chem Lett 1: 290-294 (2010) Article DOI: 10.1021/ml1000855 BindingDB Entry DOI: 10.7270/Q29G5NZJ
					More data for this Ligand-Target Pair