BindingDB PrimarySearch

Found 4 hits Enz. Inhib. hit(s) with Target = 'Furin' and Ligand = 'BDBM50399746'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Furin (Homo sapiens (Human))	BDBM50399746 (CHEMBL2179435) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Inhibition of human recombinant furin expressed in drosophila schneider 2 cells using pyroGlu-Arg-Thr-Lys-Arg-AMC as substrate after 1 hr				J Med Chem 57: 98-109 (2014) Article DOI: 10.1021/jm401457n BindingDB Entry DOI: 10.7270/Q2S1840S
Universit£ de Sherbrooke Curated by ChEMBL					More data for this Ligand-Target Pair
Furin (Homo sapiens (Human))	BDBM50399746 (CHEMBL2179435) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant furin expressed in Drosophila S2 cells using pyroGlu-Arg-Val-Lys-Arg-methyl-coumaryl-7-amide as substrate...				J Med Chem 55: 10501-11 (2012) Article DOI: 10.1021/jm3011178 BindingDB Entry DOI: 10.7270/Q2NV9KDZ
Universit£ de Sherbrooke Curated by ChEMBL					More data for this Ligand-Target Pair
Furin (Homo sapiens (Human))	BDBM50399746 (CHEMBL2179435) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Sherbrooke Curated by ChEMBL					Assay Description Inhibition of recombinant human furin expressed in S2 insect cells using pyroGlu-Arg-Thr-Lys-Arg-AMC peptide as substrate after 1 hr by spectrofluoro...				J Med Chem 61: 8457-8467 (2018) Article DOI: 10.1021/acs.jmedchem.8b01144 BindingDB Entry DOI: 10.7270/Q2SJ1P8H
Universit£ de Sherbrooke Curated by ChEMBL					More data for this Ligand-Target Pair
Furin (Homo sapiens (Human))	BDBM50399746 (CHEMBL2179435) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00518 BindingDB Entry DOI: 10.7270/Q26H4NG9
TBA					More data for this Ligand-Target Pair