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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fusion glycoprotein F0' and Ligand = 'BDBM50542625'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Fusion glycoprotein F0


(Human respiratory syncytial virus)		BDBM50542625
PNG
(CHEMBL4642110)
Show SMILES OCCCCn1c(Cn2c3cnccc3n(C3CC3)c2=O)cc2cc(Br)ccc12
Show InChI InChI=1S/C22H23BrN4O2/c23-16-3-6-19-15(11-16)12-18(25(19)9-1-2-10-28)14-26-21-13-24-8-7-20(21)27(22(26)29)17-4-5-17/h3,6-8,11-13,17,28H,1-2,4-5,9-10,14H2
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.30n/an/an/an/a



Janssen Pharmaceutical Companies of Johnson & Johnson

Curated by ChEMBL


Assay Description
Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...

J Med Chem 63: 8046-8058 (2020)


Article DOI: 10.1021/acs.jmedchem.0c00226
BindingDB Entry DOI: 10.7270/Q27H1P5V
More data for this
Ligand-Target Pair