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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fusion glycoprotein F0' and Ligand = 'BDBM50542653'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Fusion glycoprotein F0


(Human respiratory syncytial virus)		BDBM50542653
PNG
(CHEMBL4634123)
Show SMILES CS(=O)(=O)CCCn1c(Cn2c3cnccc3n(CC3CC3)c2=O)cc2cc(Cl)ccc12
Show InChI InChI=1S/C23H25ClN4O3S/c1-32(30,31)10-2-9-26-19(12-17-11-18(24)5-6-20(17)26)15-28-22-13-25-8-7-21(22)27(23(28)29)14-16-3-4-16/h5-8,11-13,16H,2-4,9-10,14-15H2,1H3
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 0.398n/an/an/an/a



Janssen Pharmaceutical Companies of Johnson & Johnson

Curated by ChEMBL


Assay Description
Inhibition of GFP-fused RSV 224 fusion protein infected in human HeLa cells assessed as reduction in viral replication after 3 days by laser microsco...

J Med Chem 63: 8046-8058 (2020)


Article DOI: 10.1021/acs.jmedchem.0c00226
BindingDB Entry DOI: 10.7270/Q27H1P5V
More data for this
Ligand-Target Pair