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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'G protein-activated inward rectifier potassium channel 1' and Ligand = 'BDBM50115223'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-activated inward rectifier potassium channel 1


(Homo sapiens (Human))
BDBM50115223
PNG
(1-(5-Methyl-2-phenyl-2H-pyrazol-3-yl)-3-phenyl-ure...)
Show SMILES Cc1cc(NC(=O)Nc2ccccc2)n(n1)-c1ccccc1
Show InChI InChI=1S/C17H16N4O/c1-13-12-16(21(20-13)15-10-6-3-7-11-15)19-17(22)18-14-8-4-2-5-9-14/h2-12H,1H3,(H2,18,19,22)
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Article
PubMed
n/an/an/an/a 1.40E+3n/an/an/an/a



Northwest Agriculture& Forestry University

Curated by ChEMBL


Assay Description
Activation of GIRK1/2 (unknown origin) by thallium flux assay


Bioorg Med Chem Lett 23: 4562-6 (2013)


Article DOI: 10.1016/j.bmcl.2013.06.023
More data for this
Ligand-Target Pair
G protein-activated inward rectifier potassium channel 1


(Homo sapiens (Human))
BDBM50115223
PNG
(1-(5-Methyl-2-phenyl-2H-pyrazol-3-yl)-3-phenyl-ure...)
Show SMILES Cc1cc(NC(=O)Nc2ccccc2)n(n1)-c1ccccc1
Show InChI InChI=1S/C17H16N4O/c1-13-12-16(21(20-13)15-10-6-3-7-11-15)19-17(22)18-14-8-4-2-5-9-14/h2-12H,1H3,(H2,18,19,22)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/an/an/a 1.40E+3n/an/an/an/a



Vanderbilt University

Curated by ChEMBL


Assay Description
Activation of GIRK1/2 (unknown origin) by cell-based thallium flux assay


Bioorg Med Chem Lett 23: 5195-8 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.002
More data for this
Ligand-Target Pair