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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'G protein-activated inward rectifier potassium channel 1' and Ligand = 'BDBM50439415'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G protein-activated inward rectifier potassium channel 1


(Homo sapiens (Human))
BDBM50439415
PNG
(CHEMBL2420549)
Show SMILES CN(C)S(=O)(=O)c1cc(NC(=O)Nc2cccc(c2)C#N)ccc1C
Show InChI InChI=1S/C17H18N4O3S/c1-12-7-8-15(10-16(12)25(23,24)21(2)3)20-17(22)19-14-6-4-5-13(9-14)11-18/h4-10H,1-3H3,(H2,19,20,22)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 3.90E+3n/an/an/an/a



Vanderbilt University

Curated by ChEMBL


Assay Description
Activation of GIRK1/2 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay


Bioorg Med Chem Lett 23: 5195-8 (2013)


Article DOI: 10.1016/j.bmcl.2013.07.002
BindingDB Entry DOI: 10.7270/Q28K7BG1
More data for this
Ligand-Target Pair