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Found 1 hit Enz. Inhib. hit(s) with Target = 'G protein-activated inward rectifier potassium channel 4' and Ligand = 'BDBM50532005'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
G protein-activated inward rectifier potassium channel 4


(Homo sapiens (Human))		BDBM50532005
PNG
(CHEMBL4543208)
Show SMILES COc1ccc(cc1)-c1nnn(CC(=O)Nc2cc(C)nn2C2CCCCC2)n1
Show InChI InChI=1S/C20H25N7O2/c1-14-12-18(27(23-14)16-6-4-3-5-7-16)21-19(28)13-26-24-20(22-25-26)15-8-10-17(29-2)11-9-15/h8-12,16H,3-7,13H2,1-2H3,(H,21,28)
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PC cid
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Article
PubMed
n/an/an/an/a 779n/an/an/an/a



University of Nebraska Medical Center

Curated by ChEMBL


Assay Description
Activation of human GIRK1/4 expressed in HEK293 cells co-expressing rat mGlu8 by thallium flux assay

Bioorg Med Chem Lett 29: 791-796 (2019)


Article DOI: 10.1016/j.bmcl.2019.01.027
BindingDB Entry DOI: 10.7270/Q2BV7M47
More data for this
Ligand-Target Pair