Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'G protein-activated inward rectifier potassium channel 4' and Ligand = 'BDBM50532017'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human))	BDBM50532017 (CHEMBL4529580) Show SMILES Cc1cc(NC(=O)Cn2nnc(n2)-c2ccc(cc2)C(F)(F)F)n(n1)C1CCCCC1 Show InChI InChI=1S/C20H22F3N7O/c1-13-11-17(30(26-13)16-5-3-2-4-6-16)24-18(31)12-29-27-19(25-28-29)14-7-9-15(10-8-14)20(21,22)23/h7-11,16H,2-6,12H2,1H3,(H,24,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	448	n/a	n/a	n/a	n/a
University of Nebraska Medical Center Curated by ChEMBL					Assay Description Activation of human GIRK1/4 expressed in HEK293 cells co-expressing rat mGlu8 by thallium flux assay				Bioorg Med Chem Lett 29: 791-796 (2019) Article DOI: 10.1016/j.bmcl.2019.01.027 BindingDB Entry DOI: 10.7270/Q2BV7M47
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