Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'G-protein coupled receptor 6' and Ligand = 'BDBM190932'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 6 (Homo sapiens (Human))	BDBM190932 (US10077266, Example 43 | US9181249, 43 | US9708313...) Show SMILES CC(C)Nc1nc2CCN(C(C)c2nc1N1CCC(CC1)Oc1ccc(F)cc1F)C(=O)C(F)F Show InChI InChI=1S/C24H29F4N5O2/c1-13(2)29-22-23(31-20-14(3)33(24(34)21(27)28)11-8-18(20)30-22)32-9-6-16(7-10-32)35-19-5-4-15(25)12-17(19)26/h4-5,12-14,16,21H,6-11H2,1-3H3,(H,29,30)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.116	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...				US Patent US9181249 (2015) BindingDB Entry DOI: 10.7270/Q2HM577D
					More data for this Ligand-Target Pair
G-protein coupled receptor 6 (Homo sapiens (Human))	BDBM190932 (US10077266, Example 43 | US9181249, 43 | US9708313...) Show SMILES CC(C)Nc1nc2CCN(C(C)c2nc1N1CCC(CC1)Oc1ccc(F)cc1F)C(=O)C(F)F Show InChI InChI=1S/C24H29F4N5O2/c1-13(2)29-22-23(31-20-14(3)33(24(34)21(27)28)11-8-18(20)30-22)32-9-6-16(7-10-32)35-19-5-4-15(25)12-17(19)26/h4-5,12-14,16,21H,6-11H2,1-3H3,(H,29,30)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...				US Patent US9708313 (2017) BindingDB Entry DOI: 10.7270/Q2ZP4858
					More data for this Ligand-Target Pair
G-protein coupled receptor 6 (Homo sapiens (Human))	BDBM190932 (US10077266, Example 43 | US9181249, 43 | US9708313...) Show SMILES CC(C)Nc1nc2CCN(C(C)c2nc1N1CCC(CC1)Oc1ccc(F)cc1F)C(=O)C(F)F Show InChI InChI=1S/C24H29F4N5O2/c1-13(2)29-22-23(31-20-14(3)33(24(34)21(27)28)11-8-18(20)30-22)32-9-6-16(7-10-32)35-19-5-4-15(25)12-17(19)26/h4-5,12-14,16,21H,6-11H2,1-3H3,(H,29,30)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...				US Patent US10077266 (2018) BindingDB Entry DOI: 10.7270/Q2T155PB
					More data for this Ligand-Target Pair