Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'G-protein coupled receptor 6' and Ligand = 'BDBM191023'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 6 (Homo sapiens (Human))	BDBM191023 (US10077266, Example 135 | US9181249, 135 | US97083...) Show SMILES CC(=O)N1CCc2nc(N3CCN(Cc4ccc(F)cc4F)CC3)c(NC3CCC3)nc2C1 Show InChI InChI=1S/C24H30F2N6O/c1-16(33)32-8-7-21-22(15-32)28-23(27-19-3-2-4-19)24(29-21)31-11-9-30(10-12-31)14-17-5-6-18(25)13-20(17)26/h5-6,13,19H,2-4,7-12,14-15H2,1H3,(H,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0437	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...				US Patent US9181249 (2015) BindingDB Entry DOI: 10.7270/Q2HM577D
					More data for this Ligand-Target Pair
G-protein coupled receptor 6 (Homo sapiens (Human))	BDBM191023 (US10077266, Example 135 | US9181249, 135 | US97083...) Show SMILES CC(=O)N1CCc2nc(N3CCN(Cc4ccc(F)cc4F)CC3)c(NC3CCC3)nc2C1 Show InChI InChI=1S/C24H30F2N6O/c1-16(33)32-8-7-21-22(15-32)28-23(27-19-3-2-4-19)24(29-21)31-11-9-30(10-12-31)14-17-5-6-18(25)13-20(17)26/h5-6,13,19H,2-4,7-12,14-15H2,1H3,(H,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited US Patent					Assay Description This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...				US Patent US9708313 (2017) BindingDB Entry DOI: 10.7270/Q2ZP4858
					More data for this Ligand-Target Pair
G-protein coupled receptor 6 (Homo sapiens (Human))	BDBM191023 (US10077266, Example 135 | US9181249, 135 | US97083...) Show SMILES CC(=O)N1CCc2nc(N3CCN(Cc4ccc(F)cc4F)CC3)c(NC3CCC3)nc2C1 Show InChI InChI=1S/C24H30F2N6O/c1-16(33)32-8-7-21-22(15-32)28-23(27-19-3-2-4-19)24(29-21)31-11-9-30(10-12-31)14-17-5-6-18(25)13-20(17)26/h5-6,13,19H,2-4,7-12,14-15H2,1H3,(H,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
TAKEDA PHARMACEUTICAL COMPANY LIMITED US Patent					Assay Description This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...				US Patent US10077266 (2018) BindingDB Entry DOI: 10.7270/Q2T155PB
					More data for this Ligand-Target Pair