Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'G-protein coupled receptor 84' and Ligand = 'BDBM50239190'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 84 (Homo sapiens (Human))	BDBM50239190 (CHEMBL4100658) Show SMILES Clc1ccc2c(Cc3c[nH]c4cc(Cl)ccc34)c[nH]c2c1 Show InChI InChI=1S/C17H12Cl2N2/c18-12-1-3-14-10(8-20-16(14)6-12)5-11-9-21-17-7-13(19)2-4-15(11)17/h1-4,6-9,20-21H,5H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...				J Med Chem 63: 2391-2410 (2020) Article DOI: 10.1021/acs.jmedchem.9b01339 BindingDB Entry DOI: 10.7270/Q2FJ2M3Q
					More data for this Ligand-Target Pair
G-protein coupled receptor 84 (Homo sapiens (Human))	BDBM50239190 (CHEMBL4100658) Show SMILES Clc1ccc2c(Cc3c[nH]c4cc(Cl)ccc34)c[nH]c2c1 Show InChI InChI=1S/C17H12Cl2N2/c18-12-1-3-14-10(8-20-16(14)6-12)5-11-9-21-17-7-13(19)2-4-15(11)17/h1-4,6-9,20-21H,5H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Agonist activity at Gi coupled human GPR84 expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins in pres...				J Med Chem 60: 3636-3655 (2017) Article DOI: 10.1021/acs.jmedchem.6b01593 BindingDB Entry DOI: 10.7270/Q289180W
					More data for this Ligand-Target Pair
G-protein coupled receptor 84 (Homo sapiens (Human))	BDBM50239190 (CHEMBL4100658) Show SMILES Clc1ccc2c(Cc3c[nH]c4cc(Cl)ccc34)c[nH]c2c1 Show InChI InChI=1S/C17H12Cl2N2/c18-12-1-3-14-10(8-20-16(14)6-12)5-11-9-21-17-7-13(19)2-4-15(11)17/h1-4,6-9,20-21H,5H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.34E+3	n/a	n/a	n/a	n/a
University of Bonn Curated by ChEMBL					Assay Description Agonist activity at human GPR84 expressed in CHO cells assessed as beta-arrestin recruitment after 90 mins by beta-galactosidase complementation assa...				J Med Chem 60: 3636-3655 (2017) Article DOI: 10.1021/acs.jmedchem.6b01593 BindingDB Entry DOI: 10.7270/Q289180W
					More data for this Ligand-Target Pair