Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GTPase KRas (Homo sapiens (Human)) | BDBM50549223 (CHEMBL4796065) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of C-terminal Avi-tagged biotinylated KRas G12D mutant (1 to 169 residues) (unknown origin) expressed in Escherichia coli assessed as redu... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01312 BindingDB Entry DOI: 10.7270/Q2T1578S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
GTPase KRas (Homo sapiens (Human)) | BDBM50549223 (CHEMBL4796065) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to GCP-KRAS G12D (unknown origin) by isothermal titration calorimetry | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01312 BindingDB Entry DOI: 10.7270/Q2T1578S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |