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Found 1 hit Enz. Inhib. hit(s) with Target = 'Gag-Pol polyprotein [489-587]' and Ligand = 'BDBM1224'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gag-Pol polyprotein [489-587]


(Human immunodeficiency virus type 1)		BDBM1224
PNG
(2-Aminobenzyl-Substituted AHPPA deriv. 42 | benzyl...)
Show SMILES CC(C)(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)[C@@H](NCc1ccc(OCCN2CCOCC2)cc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12 |r|
Show InChI InChI=1S/C47H59N5O8/c1-47(2,3)43(51-46(57)60-31-34-14-8-5-9-15-34)45(56)49-38(28-32-12-6-4-7-13-32)42(54)41(44(55)50-40-37-17-11-10-16-35(37)29-39(40)53)48-30-33-18-20-36(21-19-33)59-27-24-52-22-25-58-26-23-52/h4-21,38-43,48,53-54H,22-31H2,1-3H3,(H,49,56)(H,50,55)(H,51,57)/t38-,39+,40-,41+,42+,43+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
PubMed
 9.55n/an/an/an/an/an/an/an/a



SANDOZ Forschungsinstitut Ges. m.b.H

Curated by ChEMBL


Assay Description
Inhibitory activity was determined against HIV type 1 protease

J Med Chem 38: 4917-28 (1996)


BindingDB Entry DOI: 10.7270/Q2FX7BN8
More data for this
Ligand-Target Pair