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Found 1 hit Enz. Inhib. hit(s) with Target = 'Gag-Pol polyprotein [489-587]' and Ligand = 'BDBM50287002'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gag-Pol polyprotein [489-587]


(Human immunodeficiency virus type 1)		BDBM50287002
PNG
(6-(3-Dimethylamino-phenyl)-4-hydroxy-3-(2-isopropy...)
Show SMILES CC(C)c1ccccc1Sc1c(O)cc(oc1=O)-c1cccc(c1)N(C)C
Show InChI InChI=1S/C22H23NO3S/c1-14(2)17-10-5-6-11-20(17)27-21-18(24)13-19(26-22(21)25)15-8-7-9-16(12-15)23(3)4/h5-14,24H,1-4H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
n/an/a 114n/an/an/an/a4.7n/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against purified HIV-1 protease (BH10) at a pH of 4.7 and a final enzyme concentration of 0.45-1.1 nM

Bioorg Med Chem Lett 6: 1099-1104 (1996)


Article DOI: 10.1016/0960-894X(96)00180-1
BindingDB Entry DOI: 10.7270/Q2QV3MGM
More data for this
Ligand-Target Pair