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Found 1 hit Enz. Inhib. hit(s) with Target = 'Gag-Pol polyprotein [588-1027]/[588-1147]' and Ligand = 'BDBM2326'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Gag-Pol polyprotein [588-1027]/[588-1147]


(Human immunodeficiency virus type 1)
BDBM2326
PNG
(6-(1-phenylpropyl)-2-(propan-2-ylsulfanyl)-3,4-dih...)
Show SMILES CCC(c1ccccc1)c1cc(=O)[nH]c(SC(C)C)n1
Show InChI InChI=1S/C16H20N2OS/c1-4-13(12-8-6-5-7-9-12)14-10-15(19)18-16(17-14)20-11(2)3/h5-11,13H,4H2,1-3H3,(H,17,18,19)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.30E+3n/an/an/an/a7.837



Universita degli Studi di Roma La Sapienza



Assay Description
The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.


J Med Chem 44: 2544-54 (2001)


Article DOI: 10.1021/jm010853h
BindingDB Entry DOI: 10.7270/Q2CN724V
More data for this
Ligand-Target Pair