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Found 1 hit Enz. Inhib. hit(s) with Target = 'Gag-Pol polyprotein [588-1027]/[588-1147]' and Ligand = 'BDBM2778'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gag-Pol polyprotein [588-1027]/[588-1147]


(Human immunodeficiency virus type 1)		BDBM2778
PNG
(Alkenyldiarylmethane (ADAM) 20a | Alkenyldiarylmet...)
Show SMILES [#6]-[#6]-[#8]-[#6](=O)-[#6]-[#6]-[#6]\[#6]=[#6](/c1cc(-[#6])c(-[#8]-[#6])c(c1)-[#6](=O)-[#8]-[#6])-c1cc(-[#6])c(-[#8]-[#6])c(c1)-[#6](=O)-[#8]-[#6]
Show InChI InChI=1S/C28H34O8/c1-8-36-24(29)12-10-9-11-21(19-13-17(2)25(32-4)22(15-19)27(30)34-6)20-14-18(3)26(33-5)23(16-20)28(31)35-7/h11,13-16H,8-10,12H2,1-7H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 181n/an/an/an/a7.9n/a



Purdue University



Assay Description
The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.

J Med Chem 44: 4092-113 (2001)


Article DOI: 10.1021/jm010212m
BindingDB Entry DOI: 10.7270/Q2XG9PB0
More data for this
Ligand-Target Pair