Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Gag-Pol polyprotein [588-1027]/[588-1147]' and Ligand = 'BDBM2864'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM2864 (3-(5-bromopyridin-2-yl)-1-[3-(2-methoxyphenyl)-3-o...) Show SMILES COc1ccccc1C(=O)CCNC(=S)Nc1ccc(Br)cn1 Show InChI InChI=1S/C16H16BrN3O2S/c1-22-14-5-3-2-4-12(14)13(21)8-9-18-16(23)20-15-7-6-11(17)10-19-15/h2-7,10H,8-9H2,1H3,(H2,18,19,20,23)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	7.8	37
Medivir AB					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				Bioorg Med Chem Lett 10: 265-8 (2000) Article DOI: 10.1016/s0960-894x(99)00675-7 BindingDB Entry DOI: 10.7270/Q2DF6PDR
					More data for this Ligand-Target Pair