Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Gag-Pol polyprotein [588-1027]/[588-1147]' and Ligand = 'BDBM3375'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM3375 (7-{2-chloro-5-ethylimidazo[1,5-a]pyridazin-7-yl}-1...) Show SMILES CCc1nc(CCCCCCC(=O)c2ccccc2)n2nc(Cl)ccc12 Show InChI InChI=1S/C21H24ClN3O/c1-2-17-18-14-15-20(22)24-25(18)21(23-17)13-9-4-3-8-12-19(26)16-10-6-5-7-11-16/h5-7,10-11,14-15H,2-4,8-9,12-13H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	8.0	37
Glaxo Group Research Ltd.					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 3784-94 (1993) Article DOI: 10.1021/jm00076a005 BindingDB Entry DOI: 10.7270/Q2PR7T57
					More data for this Ligand-Target Pair