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Found 1 hit Enz. Inhib. hit(s) with Target = 'Gag-Pol polyprotein [588-1027]/[588-1147]' and Ligand = 'BDBM5043'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gag-Pol polyprotein [588-1027]/[588-1147]


(Human immunodeficiency virus type 1)		BDBM5043
PNG
(N-(2-{[(2Z)-5-tert-butyl-3,4-dimethyl-2,3-dihydro-...)
Show SMILES CC(=O)Nc1ccc(Cl)cc1S(=O)(=O)\N=c1/sc(c(C)n1C)C(C)(C)C
Show InChI InChI=1S/C17H22ClN3O3S2/c1-10-15(17(3,4)5)25-16(21(10)6)20-26(23,24)14-9-12(18)7-8-13(14)19-11(2)22/h7-9H,1-6H3,(H,19,22)/b20-16-
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Yamanouchi Pharmaceutical Co. Ltd



Assay Description
The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.

Bioorg Med Chem 13: 949-61 (2005)


Article DOI: 10.1016/j.bmc.2004.11.045
BindingDB Entry DOI: 10.7270/Q2C53J1Z
More data for this
Ligand-Target Pair