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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Gag-Pol polyprotein [588-1027]' and Ligand = 'BDBM27590'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gag-Pol polyprotein [588-1027]


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM27590
PNG
(2-{4-[4-(2-{[1-(4-tert-butyl-2-chlorophenyl)-1H-1,...)
Show SMILES CC(C)(C)c1ccc(c(Cl)c1)-n1nnnc1SCC(=O)Nc1ccc(cc1Cl)-c1ccc(CC(O)=O)cc1
Show InChI InChI=1S/C27H25Cl2N5O3S/c1-27(2,3)19-9-11-23(21(29)14-19)34-26(31-32-33-34)38-15-24(35)30-22-10-8-18(13-20(22)28)17-6-4-16(5-7-17)12-25(36)37/h4-11,13-14H,12,15H2,1-3H3,(H,30,35)(H,36,37)
PDB
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PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 7.70n/an/an/an/a7.437



Boehringer Ingelheim (Canada) Ltd.



Assay Description
IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...

Bioorg Med Chem Lett 19: 1199-205 (2009)


Article DOI: 10.1016/j.bmcl.2008.12.074
BindingDB Entry DOI: 10.7270/Q2ZG6QKQ
More data for this
Ligand-Target Pair