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Found 1 hit Enz. Inhib. hit(s) with Target = 'Gag-Pol polyprotein [600-1027,R876K]/[600-1155]' and Ligand = 'BDBM1600'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gag-Pol polyprotein [600-1027,R876K]/[600-1155]


(Human immunodeficiency virus type 1)		BDBM1600
PNG
(11-Cyclopropyl-5,1 l-dihydro-4-[ [(4-methoxyphenyl...)
Show SMILES COc1ccc(OCc2ccnc3N(C4CC4)c4ncccc4C(=O)Nc23)cc1
Show InChI InChI=1S/C22H20N4O3/c1-28-16-6-8-17(9-7-16)29-13-14-10-12-24-21-19(14)25-22(27)18-3-2-11-23-20(18)26(21)15-4-5-15/h2-3,6-12,15H,4-5,13H2,1H3,(H,25,27)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
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AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.04E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.

J Med Chem 38: 4839-47 (1995)


Article DOI: 10.1021/jm00024a011
BindingDB Entry DOI: 10.7270/Q2ZK5DV7
More data for this
Ligand-Target Pair