Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2' and Ligand = 'BDBM50089770'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Homo sapiens (Human))	BDBM50089770 (1-(1,3-Dihydro-isoindol-2-yl)-2-(1H-indol-3-yl)-et...) Show SMILES O=C(N1Cc2ccccc2C1)C(=O)c1c[nH]c2ccccc12 Show InChI InChI=1S/C18H14N2O2/c21-17(15-9-19-16-8-4-3-7-14(15)16)18(22)20-10-12-5-1-2-6-13(12)11-20/h1-9,19H,10-11H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Binding affinity evaluated by ability to displace [3H]Ro-151788 from recombinant human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2 expr...				Bioorg Med Chem Lett 10: 1381-4 (2000) BindingDB Entry DOI: 10.7270/Q2KD1X5T
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2 (Rattus norvegicus (Rat))	BDBM50089770 (1-(1,3-Dihydro-isoindol-2-yl)-2-(1H-indol-3-yl)-et...) Show SMILES O=C(N1Cc2ccccc2C1)C(=O)c1c[nH]c2ccccc12 Show InChI InChI=1S/C18H14N2O2/c21-17(15-9-19-16-8-4-3-7-14(15)16)18(22)20-10-12-5-1-2-6-13(12)11-20/h1-9,19H,10-11H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	224	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Pisa Curated by ChEMBL					Assay Description Inhibition of [3H]-flumazenil binding to rat alpha1-beta2-gamma2 GABA-A receptor subunits expressed in HEK293 cells				J Med Chem 44: 2286-97 (2001) BindingDB Entry DOI: 10.7270/Q2T152WS
					More data for this Ligand-Target Pair