BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Gamma-aminobutyric acid receptor subunit alpha-1' and Ligand = 'BDBM50242613'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-1 (Homo sapiens (Human))	BDBM50242613 (8-Isothiocyanato-5-methyl-6-oxo-5,6-dihydro-4H-2,5...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	878	n/a	n/a	n/a	n/a	n/a
University of Bern Curated by ChEMBL					Assay Description Displacement of [3H]Ro15-1788 from rat GABAA alpha1beta2gamma2 receptor expressed in HEK293 cells after 1 hr assessed as residual binding by liquid s...				J Biol Chem 282: 26316-25 (2007) Article DOI: 10.1074/jbc.M702153200 BindingDB Entry DOI: 10.7270/Q2PR7VR8
University of Bern Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1 (Homo sapiens (Human))	BDBM50242613 (8-Isothiocyanato-5-methyl-6-oxo-5,6-dihydro-4H-2,5...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	250	n/a	n/a	n/a	n/a
University of Bern Curated by ChEMBL					Assay Description Activity at rat wild type GABAA alpha1beta2gamma2 receptor expressed in xenopus oocytes assessed as GABA-elicited response by two electrode voltage c...				J Biol Chem 282: 26316-25 (2007) Article DOI: 10.1074/jbc.M702153200 BindingDB Entry DOI: 10.7270/Q2PR7VR8
University of Bern Curated by ChEMBL					More data for this Ligand-Target Pair