Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Gamma-aminobutyric acid receptor subunit alpha-1' and Ligand = 'BDBM50459891'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-1 (Rattus norvegicus (Rat))	BDBM50459891 (CHEMBL4229086) Show SMILES CCCCNC(=O)c1cc(ccc1O)-c1ccc(F)cc1F Show InChI InChI=1S/C17H17F2NO2/c1-2-3-8-20-17(22)14-9-11(4-7-16(14)21)13-6-5-12(18)10-15(13)19/h4-7,9-10,21H,2-3,8H2,1H3,(H,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Agonist activity at GABAA receptor in Sprague-Dawley rat forebrain membranes assessed as enhancement of [3H]muscimol binding after 2 hrs by radiometr...				Bioorg Med Chem Lett 27: 3207-3218 (2017) Article DOI: 10.1016/j.bmcl.2017.04.073 BindingDB Entry DOI: 10.7270/Q2MC92NR
					More data for this Ligand-Target Pair