Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Gamma-aminobutyric acid receptor subunit alpha-2' and Ligand = 'BDBM144231'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM144231 (US8952008, 18) Show SMILES CC(C)S(=O)(=O)c1ccc(c(c1)C#N)-c1cc(ccc1F)-c1cnnc2n(cnc12)C1CC1 Show InChI InChI=1S/C24H20FN5O2S/c1-14(2)33(31,32)18-6-7-19(16(9-18)11-26)20-10-15(3-8-22(20)25)21-12-28-29-24-23(21)27-13-30(24)17-4-5-17/h3,6-10,12-14,17H,4-5H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	296	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Limited US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW
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