Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Gamma-aminobutyric acid receptor subunit alpha-2' and Ligand = 'BDBM430025'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-2 (Homo sapiens (Human))	BDBM430025 (4-(4′-Ethanesulfonyl-6-fluoro-2′-metho...) Show SMILES CCn1ncc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1OC)S(=O)(=O)CC Show InChI InChI=1S/C22H21FN4O3S/c1-4-27-22-19(13-25-27)18(12-24-26-22)14-6-9-20(23)17(10-14)16-8-7-15(11-21(16)30-3)31(28,29)5-2/h6-13H,4-5H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
PFIZER LIMITED US Patent					Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...				US Patent US10538523 (2020) BindingDB Entry DOI: 10.7270/Q2RB771W
					More data for this Ligand-Target Pair