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Found 1 hit Enz. Inhib. hit(s) with Target = 'Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2' and Ligand = 'BDBM50112225'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2


(Homo sapiens (Human))		BDBM50112225
PNG
(6-(4-Dimethylamino-phenyl)-5-(4-methoxy-phenyl)-1-...)
Show SMILES COC(=O)c1cc(-c2ccc(OC)cc2)c(-c2ccc(cc2)N(C)C)n(C)c1=O
Show InChI InChI=1S/C23H24N2O4/c1-24(2)17-10-6-16(7-11-17)21-19(15-8-12-18(28-4)13-9-15)14-20(23(27)29-5)22(26)25(21)3/h6-14H,1-5H3
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Similars
PubMed
 250n/an/an/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity by displacement of [3H]-Ro-15-1788 from recombinant human gamma-aminobutyric-acid A receptor alpha3,beta3,gamma2 stably expressed in...

J Med Chem 45: 1887-900 (2002)


BindingDB Entry DOI: 10.7270/Q2KP81HZ
More data for this
Ligand-Target Pair