Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Gamma-aminobutyric acid receptor subunit alpha-5' and Ligand = 'BDBM120145'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-5 (Homo sapiens (Human))	BDBM120145 (US8697696, 2) Show SMILES Cn1nnc(c1COc1cc(C(=O)NC2CCOCC2)n(C)n1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H23FN6O3/c1-26-16(20(28)22-15-7-9-29-10-8-15)11-18(24-26)30-12-17-19(23-25-27(17)2)13-3-5-14(21)6-4-13/h3-6,11,15H,7-10,12H2,1-2H3,(H,22,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	45.3	-39.0	n/a	n/a	n/a	n/a	n/a	7.5	4
Roche Palo Alto LLC US Patent					Assay Description Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell membranes, [3H]flumazenil at a conc...				US Patent US8697696 (2014) BindingDB Entry DOI: 10.7270/Q2DB80HJ
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