Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Gamma-aminobutyric acid receptor subunit alpha-5' and Ligand = 'BDBM120148'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-5 (Homo sapiens (Human))	BDBM120148 (US8697696, 5) Show SMILES Cc1nnn(c1COc1cc(C(=O)NC2(C)COC2)n(C)n1)-c1ccc(F)cc1 Show InChI InChI=1S/C19H21FN6O3/c1-12-16(26(24-22-12)14-6-4-13(20)5-7-14)9-29-17-8-15(25(3)23-17)18(27)21-19(2)10-28-11-19/h4-8H,9-11H2,1-3H3,(H,21,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	43.2	-39.1	n/a	n/a	n/a	n/a	n/a	7.5	4
Roche Palo Alto LLC US Patent					Assay Description Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell membranes, [3H]flumazenil at a conc...				US Patent US8697696 (2014) BindingDB Entry DOI: 10.7270/Q2DB80HJ
					More data for this Ligand-Target Pair