Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Gamma-aminobutyric acid receptor subunit alpha-5' and Ligand = 'BDBM120150'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-5 (Homo sapiens (Human))	BDBM120150 (US8697696, 7) Show SMILES Cc1nc(\C=C\c2c(nnn2C)-c2ccc(F)cc2)sc1C(=O)NC1CCOCC1 Show InChI InChI=1S/C21H22FN5O2S/c1-13-20(21(28)24-16-9-11-29-12-10-16)30-18(23-13)8-7-17-19(25-26-27(17)2)14-3-5-15(22)6-4-14/h3-8,16H,9-12H2,1-2H3,(H,24,28)/b8-7+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.20	-43.5	n/a	n/a	n/a	n/a	n/a	7.5	4
Roche Palo Alto LLC US Patent					Assay Description Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell membranes, [3H]flumazenil at a conc...				US Patent US8697696 (2014) BindingDB Entry DOI: 10.7270/Q2DB80HJ
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