Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gamma-secretase subunit PEN-2 (Homo sapiens (Human)) | BDBM50069985 ((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | 2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Harvard Medical School Curated by ChEMBL | Assay Description Inhibition of Amyloid-beta production in APP-transfected cells at level of gamma secretase | J Med Chem 44: 2039-60 (2001) BindingDB Entry DOI: 10.7270/Q27S7PGX | |||||||||||
More data for this Ligand-Target Pair |