Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gamma-secretase subunit PEN-2 (Homo sapiens (Human)) | BDBM50143556 ((S)-2-{(S)-2-[2-(3,5-Difluoro-phenyl)-acetylamino]...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tokyo Curated by ChEMBL | Assay Description Inhibitory activity of the compound against gamma-secretase | Bioorg Med Chem Lett 14: 1983-5 (2004) Article DOI: 10.1016/j.bmcl.2004.01.067 BindingDB Entry DOI: 10.7270/Q2R78DPT | |||||||||||
More data for this Ligand-Target Pair |