Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM103263'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C virus genotype 3a (isolate NZL1) (HCV))	BDBM103263 (US8546389, 156) Show SMILES CNC(=O)c1n(nc2cc(N(CCCNC(=O)C(C)C)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Br)cc1 Show InChI InChI=1S/C26H32BrN5O4S/c1-16(2)25(33)29-12-5-13-31(37(4,35)36)23-15-22-21(14-20(23)17-6-7-17)24(26(34)28-3)32(30-22)19-10-8-18(27)9-11-19/h8-11,14-17H,5-7,12-13H2,1-4H3,(H,28,34)(H,29,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Biota Scientific Management Pty Ltd. US Patent					Assay Description HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe...				US Patent US8546389 (2013) BindingDB Entry DOI: 10.7270/Q2DZ06XK
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus genotype 1b (isolate BK) (HCV))	BDBM103263 (US8546389, 156) Show SMILES CNC(=O)c1n(nc2cc(N(CCCNC(=O)C(C)C)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Br)cc1 Show InChI InChI=1S/C26H32BrN5O4S/c1-16(2)25(33)29-12-5-13-31(37(4,35)36)23-15-22-21(14-20(23)17-6-7-17)24(26(34)28-3)32(30-22)19-10-8-18(27)9-11-19/h8-11,14-17H,5-7,12-13H2,1-4H3,(H,28,34)(H,29,33)	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Biota Scientific Management Pty Ltd. US Patent					Assay Description HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe...				US Patent US8546389 (2013) BindingDB Entry DOI: 10.7270/Q2DZ06XK
					More data for this Ligand-Target Pair