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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM12289'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Genome polyprotein


(Hepatitis C virus (HCV genotype 1a, isolate H))		BDBM12289
PNG
(1,1-Dimethylethyl-[2-[(1R,5S)-2(S)-[[[3-amino-1-(c...)
Show SMILES CC(C)(C)OC(=O)N[C@@H](C1CCCCC1)C(=O)N1C[C@H]2[C@@H]([C@H]1C(=O)NC(CC1CCCCC1)C(=O)C(N)=O)C2(C)C |r|
Show InChI InChI=1S/C31H50N4O6/c1-30(2,3)41-29(40)34-23(19-14-10-7-11-15-19)28(39)35-17-20-22(31(20,4)5)24(35)27(38)33-21(25(36)26(32)37)16-18-12-8-6-9-13-18/h18-24H,6-17H2,1-5H3,(H2,32,37)(H,33,38)(H,34,40)/t20-,21?,22-,23-,24-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
>1.20E+4n/an/an/an/an/an/an/an/a



Schering-Plough Research Institute



Assay Description
Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...

J Med Chem 49: 6074-86 (2006)


Article DOI: 10.1021/jm060325b
BindingDB Entry DOI: 10.7270/Q2DF6PF6
More data for this
Ligand-Target Pair