Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM183526'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM183526 (US9145354, 150) Show SMILES CC[C@@H](N[C@@H](C)CC(N)=O)c1ccc(C)c(C(=O)c2ccccc2)c1F |r| Show InChI InChI=1S/C21H25FN2O2/c1-4-17(24-14(3)12-18(23)25)16-11-10-13(2)19(20(16)22)21(26)15-8-6-5-7-9-15/h5-11,14,17,24H,4,12H2,1-3H3,(H2,23,25)/t14-,17+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	25
ASTEX THERAPEUTICS LIMITED US Patent					Assay Description The HCV NS3 protease functions have been extensively studied and are considered as potential targets for antiviral therapy: see for example the many ...				US Patent US9145354 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MMZ
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