Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Genome polyprotein' and Ligand = 'BDBM203918'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C virus genotype 1b (isolate BK) (HCV))	BDBM203918 (US9242988, 27) Show SMILES CO[C@@]1(O[C@@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@H](O)C1(C)C#N)c1cnc2c(N)ncnn12 |r| Show InChI InChI=1S/C13H19N6O13P3/c1-12(5-14)9(20)7(4-29-34(24,25)32-35(26,27)31-33(21,22)23)30-13(12,28-2)8-3-16-11-10(15)17-6-18-19(8)11/h3,6-7,9,20H,4H2,1-2H3,(H,24,25)(H,26,27)(H2,15,17,18)(H2,21,22,23)/p-4/t7-,9-,12?,13+/m0/s1	PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	7.3	25
Merck Sharp & Dohme Corp. US Patent					Assay Description To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ...				US Patent US9242988 (2016) BindingDB Entry DOI: 10.7270/Q22B8WVP
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